Red Bean Natto Reduces Hyperlipidemia in Hamsters

What is it about?

The oral administration of Bacillus subtilis-fermented red bean natto extract (RBNE), a popular Asian dessert, effectively moderated the metabolism of lipids and positively affected the blood and liver profiles of hamsters fed with a high-cholesterol and high-fat diet.

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Why is it important?

RBNE significantly suppressed the increase in visceral fat mass. Additionally, RBNE appears to protect the liver and alleviate the magnitude of fatty liver development. RBNE also upregulated PPAR-alpha protein expression in the liver, suggesting that supplementation may improve lipid metabolism in part through the beta-oxidation of lipids and promotion of lipid secretion.