What is it about?

This article illustrates how genetic differences impact the metabolism of the drug exemestane among women to help guide treatment of breast cancer

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Why is it important?

Understanding the differences in the genetic makeup of individuals, such as postmenopausal women receiving treatment for breast cancer, can help us better tailor treatment and only treat those who we believe have a chance of responding to the drug therapy

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Bryana Gregory
Harding University

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This page is a summary of: Impact of the OATP1B1 c.521T>C single nucleotide polymorphism on the pharmacokinetics of exemestane in healthy post-menopausal female volunteers, Journal of Clinical Pharmacy and Therapeutics, July 2017, Wiley,
DOI: 10.1111/jcpt.12569.
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