What is it about?
Homocysteine (Hcy) is an amino acid that is broken down by vitamin B6, and B12. It is considered and inflammatory marker and implicated in the development of heart diseases. The present study was conducted to assess the effect of periodontal disease and periodontal therapy on plasma Hcy.
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Why is it important?
Plasma Hcy levels were found to increase with periodontal inflammation and decrease after therapy. This indicates a direct relationship of Hcy with periodontal diseases. In case the patient demonstrating high plasma Hcy values also has periodontal/gum diseases, they should be treated with periodontal therapy to lower the Hcy levels. xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Perspectives
As the internal surface of deepened gingival sulcus (pockets) gets inflamed, a lot of inflammatory mediators are released. They circulate in the blood stream, thus increasing the overall inflammatory load of the system. Hence, control of gum inflammation becomes essential to decrease the systemic inflammatory load, and prevent any untoward outcomes.
Smiti Bhardwaj
Maulana Azad Institute of Dental Sciences
Read the Original
This page is a summary of: Effect of non-surgical periodontal therapy on plasma homocysteine levels in Indian population with chronic periodontitis: a pilot study, Journal Of Clinical Periodontology, March 2015, Wiley,
DOI: 10.1111/jcpe.12374.
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