What is it about?

This publications reports the genotype frequencies of certain drug metabolizing enzymes and drug transporters among a set of Pakistani breast cancer patients. It's the first such report from the region.

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Why is it important?

Differences in genotyping frequencies can account for differences in drug response. Thus, it forms the basis of tailored drug therapy.

Perspectives

This is the first study from Pakistan in this regard.

Dr Nasir Ali Afsar
Jinnah Medical & Dental College Karachi; Alfaisal University Riyadh.

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This page is a summary of: Genotype Frequencies of Selected Drug Metabolizing Enzymes and ABC Drug Transporters among Breast Cancer Patients on FAC Chemotherapy, Basic & Clinical Pharmacology & Toxicology, January 2010, Wiley,
DOI: 10.1111/j.1742-7843.2009.00531.x.
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