What is it about?
We decided to analyze this parallel IA testing strategy in terms of efficiency and accuracy to detect true HIV infection.
Featured Image
Why is it important?
To evaluate whether we could use concordance and or levels of reactivity on both IAs as an accurate predictor of true HIV infection status for prevalence and incidence analyses.
Perspectives
This study presents a systematic analysis of results of serologic screening of more than 2.5 million blood donations tested in parallel for HIV antibodies by two different screening tests. Reactivity by two screening assays, employed sequentially in a confirmatory algorithm, would have predictive positive value higher than 90% if the assays are selected from different manufacturers.
Dr Cesar de Almeida-Neto
Faculty of Medicine, University of São Paulo
Read the Original
This page is a summary of: Performance of parallel screening of Brazilian blood donors with two human immunodeficiency virus immunoassays: implications for sequential immunoassay testing algorithms in other countries, Transfusion, January 2011, Wiley,
DOI: 10.1111/j.1537-2995.2010.02773.x.
You can read the full text:
Contributors
The following have contributed to this page
