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Arachidonic acid enhances proton channel gating similarly to PMA. The data are mostly consistent with the proposal by Henderson et al (1993) that AA is the final step in the signaling pathways that activate both NADPH oxidase and proton channels.
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This page is a summary of: Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid, The Journal of Physiology, September 2001, Wiley,
DOI: 10.1111/j.1469-7793.2001.00783.x.
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