What is it about?
For determining the toxic effect of heavy metals on dermatophytes, eight heavy metals were tested using colony diameter method. Cadmium showed high toxicity effects on isolated fungi at minimal inhibitory concentration of 27 lg ml)1 for Trichophyton mentagrophytes and of 20 lg ml)1 for Epidermophyton floccosum, while iron enhanced dermatophytic growth. Other heavy metals revealed variable effect on isolated fungi. Susceptibility of E. floccosum to the activity of tested metals was greater than those of T. mentagrophytes. In conclusion, cadmium and silver are regarded to be the effective metals to prevent the development of two isolated species of dermatophytes. Growth of fungi in the presence of iron was greater than control.
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Why is it important?
For determining the toxic effect of heavy metals on dermatophytes which can use as treatment
Perspectives
discover the most effective types of heavy metals will encourage us to use it as antidermatophytic drugs. The toxicity of heavy metals for human suppose to be very low due to the restricted location of dermatophytosis on outer skin layers.
Professor Ali Abdul Hussein S. AL-Janabi
collage of Medicine, university of karbala
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This page is a summary of: Toxic effect of heavy metals on dermatophytes, Mycoses, April 2010, Wiley,
DOI: 10.1111/j.1439-0507.2010.01876.x.
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