What is it about?
We have reported the CAPS dressing and traditional dressing containing carboxymethyl cellulose (CMC) for wound healing and scar tissue formation in a burn model of rat and swine. Our results revealed that the efficacy of the dressing containing CAPS for wound repair post burn was better than the CMC dressing with respect to natural wound healing and scar formation. The polysaccharide-enriched dressing exerted an antimicrobial effect on burn wounds, regulated the inflammatory response, and stimulated anti-inflammatory cytokine release.
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Why is it important?
We suggest that a polysaccharide-enriched dressing outperformed a traditional dressing in reducing wound size, minimizing hypertrophic scar formation, regulating cytokines, and maximizing antimicrobial effects.
Perspectives
I hope this article lead more clinicians choose improved alginate dressing, because of a good dressing should be easy to handle, prevent infection/inflammation, alleviate pain, have no toxicity, permit easy and early mobilization, cause no allergic reactions, have low cost, and form quick and solid healing with an acceptable scar.
Juin-Hong Cherng
National Defense Medical Center
Read the Original
This page is a summary of: Enhanced wound-healing performance of a phyto-polysaccharide-enriched dressing - a preclinical small and large animal study, International Wound Journal, September 2017, Wiley,
DOI: 10.1111/iwj.12813.
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