What is it about?
This study performed comparison of the distribution and density of LGR5-positive stem cells in conventional adenomas vs. serrated adenomas of the colorectum.
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Why is it important?
This study elucidates whether LGR5+ stem cells contributes similarly to both conventional adenomas and serrated adenomas.
Perspectives
Serrated neoplasia pathway is different from classical adenoma-carcinoma sequence in terms of participation of LGR5-positive cells.
Professor Gyeong-Hoon Kang
Seoul National University Hospital
Read the Original
This page is a summary of: Distribution of intestinal stem cell markers in colorectal precancerous lesions, Histopathology, September 2015, Wiley,
DOI: 10.1111/his.12787.
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