What is it about?
Circular RNAs (circRNAs) are a class of new found RNA molecules that have a special covalent loop structure without 5’ cap and 3’ tail.
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Why is it important?
By severing as sponge of microRNAs, interacting with long non-coding RNAs, mRNA, or proteins, circRNAs regulate gene expression at transcriptional and post-transcriptional levels and contribute carcinogenesis.
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This page is a summary of: Circular RNAs: Biogenesis, properties, roles, and their relationships with liver diseases, Hepatology Research, March 2017, Wiley,
DOI: 10.1111/hepr.12871.
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