What is it about?

One of the first RCTs to show metabolic effects in detail following per oral administration of L reuteri DSM 17938 or placebo in type 2 diabetes patients. Diversity of gut microbiota may play a for getting a positive effect on metabolic control after L reuteri DSM 17938.

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Why is it important?

This study shows that the metabolic response can vary considerably in type 2 diabetes patients following probiotic treatment. Our results suggest that it is important to know the gut microbiota composition to predict whether there will be a positive metabolic effect after L reuteri DSM 17938.

Perspectives

Larger randomized clinical trials using Lactobacillus strains are needed to better understand if positive metabolic long term effects may be achieved in human subjects.

Prof Per-Anders Jansson
University of Gothenburg

Read the Original

This page is a summary of: Metabolic effects ofLactobacillus reuteriDSM 17938 in people with type 2 diabetes: A randomized controlled trial, Diabetes Obesity and Metabolism, February 2017, Wiley,
DOI: 10.1111/dom.12861.
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