What is it about?

Randomized double-blind controlled trial assessed patients undergoing bronchoscopy and receiving lidocaine alone (C) or combined with dexmedetomidine (D) or alfentanil (A). Tolerance was assessed using the bronchoscopy score, and level of sedation was assessed using the Nursing Instrument for the Communication of Sedation. Safety was evaluated in terms of pulmonary function and vital signs

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Why is it important?

First to compare the feasibility and tolerability of three different sedation regimens in FB and to determine the most appropriate one in selected patient profiles

Perspectives

The three regimens were found suitable but each was more appropriate in certain patient profiles. The proposed protocol is a first step towards standardizing sedation practice in FB in a patient-tailored manner. A more comprehensive and detailed protocol including other sedative agents with their corresponding doses should be developed.

Moussa Riachy
Saint Joseph University- Faculty of Medicine

Read the Original

This page is a summary of: A randomized double-blind controlled trial comparing three sedation regimens during flexible bronchoscopy: Dexmedetomidine, alfentanil and lidocaine, The Clinical Respiratory Journal, August 2017, Wiley,
DOI: 10.1111/crj.12669.
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