Deflazacort hypersensitivity: a difficult-to-manage case of systemic allergic dermatitis and literature review

What is it about?

Management of corticosteroid hypersensitivity is not easy, and the choice of an alternative CS is difcult,owing to the high frequency of cross-reactions. Deflazacort has been reported to be a safe alternative in subjects with CS hypersensitivity, and reports of deflazacort hypersensitivity are rare. Here, we report a difficult-to-manage case of systemic allergic dermatitis caused by deflazacort.

Featured Image

Why is it important?

Our study highlights the need for a review of CS cross-reaction patterns, because none of the current proposals seems to explain the observed clinical findings.