Influence of hydroxyapatite granule size, porosity and crystallinity on tissue reaction in vivo

What is it about?

The aim of this study was the synthesis and analysis of the tissue reaction to three different Hydroxyapatite (HA) based bone substitute materials differing only in granule size, porosity and crystallinity through an animal experimental model at 60 days.

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Why is it important?

The tendency for the density was to increase with the increasing annealing temperature; in this way it was possible to observe that the sample that shows highest crystallinity and crystal size corresponding to that of group I. The SEM morphological examination showed that group III implant showed numerous resorption regions, group II implant presented an average resorption rate of all the implants. The group I displayed smoother surface features, in comparison with the other two implants.