What is it about?
This paper described the path that the Zika virus made from its discovery back in 1947 in Uganda until the current outbreak based on the public data available at the time. The work also shown modifications on regions of the viral genetic code that could be key to explain the changes on the disease preference to host as well as to why the birth defects are happening.
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Why is it important?
The paper show novel insights on how the virus may be affecting the human body by inducing an autoimmune response against proteins related to neurological development. It also shown how the virus may have increased its preference to human cells, more specifically cells with abundance of the Musashi-1 protein.
Read the Original
This page is a summary of: Molecular evolution of Zika virus as it crossed the Pacific to the Americas, Cladistics, December 2016, Wiley,
DOI: 10.1111/cla.12178.
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