What is it about?
The diagnosis of systemic mastocytosis is difficult. The sensitivity of major diagnosis criterion for systemic mastocytosis is of 68% to 80%.
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Why is it important?
A level of bone marrow tryptase of 50 µg/L or more is highly suggestive of systemic mastocytosis, with a sensitivity over 93% and a specificity of 90.0%.
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This page is a summary of: Bone marrow tryptase as a possible diagnostic criterion for adult systemic mastocytosis, Clinical & Experimental Allergy, December 2015, Wiley,
DOI: 10.1111/cea.12627.
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