What is it about?
In the mid-20th century, DNA sequences were believed to be the only genetic material in all living things. Today, multiple examples of heredity without differences in DNA sequence are known, but they are not covered by traditional genetic concepts. As a result, these concepts require now significant recomprehension and approval. In this paper, a general view on both canonical and all 'non-canonical' mechanisms of inheritance is presented.
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Why is it important?
We propose a unique approach allowing a simple and useful description of any 'non-canonical' hereditary factors irrespective to their molecular nature. This approach successfully resolves multiple conceptual and terminological confusions in current genetics.
Perspectives
I hope this paper will provide the first steps towards novel fundamental genetic concepts equally covering all the mechanisms of inheritance, both canonical and 'non-canonical'.
Oleg Tikhodeyev
Saint Petersburg State University
Read the Original
This page is a summary of: The mechanisms of epigenetic inheritance: how diverse are they?, Biological Reviews, May 2018, Wiley,
DOI: 10.1111/brv.12429.
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