Factors influencing biased agonism in recombinant cells expressing the human α1A -adrenoceptor

What is it about?

Biased agonism is a term that refers to the finding that different drugs acting at the same receptor can produce different effects. This property can be used to enhance the specificity of the drug or to decrease side effects. We show that determination of bias can be complicated by drugs acting at other receptors or sites in a cell rather than their primary target.

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