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What is it about?
The study evaluates the long-term impact of using intraoperative cone-beam computed tomography (CBCT) during percutaneous nephrolithotomy (PCNL) on stone-related morbidity and stone-free rates. A retrospective analysis of a randomized controlled trial shows that CBCT improves stone clearance by detecting and removing residual fragments during the procedure, reducing stone-related events (SREs) like re-interventions and hospital visits. Over an 18-month period, the CBCT group had a 10% lower occurrence of SREs compared to the conventional PCNL group, although this difference wasn't statistically significant. However, the CBCT group had a significantly lower rate of detecting new or residual fragments larger than 4 mm. The findings suggest that intraoperative CBCT may lead to fewer SREs and higher stone-free rates, indicating potential long-term benefits despite initial drawbacks like higher costs and longer procedures.
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Why is it important?
This research is important because it evaluates the long-term benefits of using intraoperative cone-beam computed tomography (CBCT) during percutaneous nephrolithotomy (PCNL), a standard treatment for complex renal stones. Understanding the impact of CBCT on stone clearance and stone-related morbidity can lead to improved patient outcomes by reducing the need for additional procedures, emergency visits, and hospital admissions. The study highlights the potential for CBCT to increase stone-free rates and decrease stone-related events (SREs), which can enhance patient quality of life and reduce healthcare costs associated with multiple interventions. This information is crucial for informing clinical practices and optimizing the management of patients with complex urolithiasis. Key Takeaways: 1. Improved Stone-Free Rates: The study found that the use of intraoperative CBCT during PCNL significantly improves stone-free rates by allowing for the detection and removal of residual fragments that may not be visible with conventional methods. 2. Reduction in Stone-Related Events: Over an 18-month follow-up period, patients who underwent PCNL with CBCT experienced a 10% reduction in stone-related events (SREs) compared to those who had conventional PCNL, indicating a potential long-term benefit in reducing morbidity. 3. Cost and Quality of Life Implications: By potentially reducing the need for re-interventions and hospital visits, intraoperative CBCT during PCNL could lead to lower healthcare costs and improve the quality of life for patients with complex renal stones.
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This page is a summary of: Longer‐term effects of intraoperative cone‐beam computed tomography in percutaneous nephrolithotomy: 18‐month retrospective randomised controlled trial analysis, BJU International, July 2025, Wiley,
DOI: 10.1111/bju.16859.
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