Comparing Gemcitabine and Docetaxel to BCG for High-Risk Bladder Cancer

What is it about?

A multi-institutional database of 858 patients who underwent robot-assisted radical cystectomy (RARC) with intracorporeal neobladder was created to study postoperative complications. The type and severity of complications were classified using the Clavien-Dindo classification system. The most common complications were urinary tract infections (UTIs), with a high rate of early complications. Severe complications were less common but more likely to occur after neoadjuvant therapy. The study aimed to improve perioperative management and reduce RARC morbidity by identifying areas in need of further research.

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Why is it important?

This research is important because it provides valuable insights into the type and severity of complications that occur after robot-assisted radical cystectomy (RARC) with intracorporeal neobladder. Understanding these complications is crucial to improving perioperative management, identifying areas in need of further research, and ultimately reducing the morbidity rate associated with RARC. Key Takeaways: 1. RARC with intracorporeal neobladder is a technically challenging procedure associated with high overall postoperative morbidity. 2. Understanding the most common complications associated with RARC is essential to improve perioperative management and reduce the morbidity rate. 3. This study aimed to characterize the type of complications occurring after RARC with intracorporeal neobladder, involving 858 patients from 16 high-volume European centers between 2003 and 2022. 4. UTI was the most common complication, occurring in 20% of patients within the first month post-surgery, with most cases being non-severe. 5. Urinary leakage/fistula and urinary device complication were the most common severe early complications, while ureteric stricture and lymphocele/lymphorrea were the most common severe late complications. 6. The rate of complications was highest in the first month post-surgery, with the majority of complications being non-severe.