What is it about?

This short review summarizes the various investigated strategies to reverse or prevent HGPS disease progression in vitro and in vivo

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Why is it important?

. In particular, this article presents recent data evaluating HGPS treatments targeting the posttranslational processing of progerin.

Perspectives

It helps to summerize the possible treatment method of HGPS.

xue chen
Huazhong University of Science and Technology

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This page is a summary of: Status of treatment strategies for Hutchinson–Gilford progeria syndrome with a focus on prelamin: A posttranslational modification, Basic & Clinical Pharmacology & Toxicology, July 2022, Wiley,
DOI: 10.1111/bcpt.13770.
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