What is it about?
Epigenetic errors frequently observed in cloned animals are not transmitted to the next generation. Here we report that these errors are erased during gametogenesis.
Featured Image
Why is it important?
This is the first molecular evidence that no epigenetic errors are found in cloned cattle gametes (oocytes / sperm). These findings contribute to the soundness of cloned cattle offspring.
Perspectives
As this work is not genome-wide approach, it is needed to analyze DNA methylome of cloned cattle germ cells to confer the soundness of cloned cattle offspring.
Dr. Masahiro Kaneda
Tokyo University of Agriculture and Technology
Read the Original
This page is a summary of: Proper reprogramming of imprinted and non-imprinted genes in cloned cattle gametogenesis, Animal Science Journal, June 2017, Wiley,
DOI: 10.1111/asj.12846.
You can read the full text:
Contributors
The following have contributed to this page
