What is it about?

This study provides a new evidence on temporal relationship by which diabetes promotes the development of hepatocellular carcinoma in patients with chronic hepatitis B, which could infer a causal relationship, rather than only association.

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Why is it important?

Chronic hepatitis B patients who develop diabetes during follow-up are at an increased risk of hepatocellular carcinoma over time and should receive active glycemic control to improve outcome.

Perspectives

The development of diabetes in chronic hepatitis B patients promotes development of hepatocellular carcinoma. Thus, active prevention of diabetes with lifestyle modification and optimal glycemic control in those with diabetes is important to improve the outcome of these patients.

Dr Yi-Wen Huang
Cathay General Hospital Medical Center

Read the Original

This page is a summary of: Increased risk of hepatocellular carcinoma in chronic hepatitis B patients with new onset diabetes: a nationwide cohort study, Alimentary Pharmacology & Therapeutics, April 2015, Wiley,
DOI: 10.1111/apt.13191.
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