Tezepelumab, an anti-TSLP antibody, enhances steroid sensitivity in patients with severe asthma.

What is it about?

Tezepelumab, an anti-TSLP antibody, reduces inflammation in asthma. In this study, it improved steroid sensitivity in severe asthma, likely by suppressing inflammatory pathways. These findings suggest tezepelumab can restore steroid response for patients who do not respond well to steroids alone.

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Photo by CNordic Nordic on Unsplash

Photo by CNordic Nordic on Unsplash

Why is it important?

For the first time, these results suggest tezepelumab can restore steroid sensitivity. This leads to better symptom control and outcomes for those with severe asthma who respond poorly to steroids alone.