What is it about?
We assessed 500 adult patients who presented with a non-purulent skin and soft tissue infection (cellulitis) to the emergency department. Four factors were associated with oral antibiotic treatment failure: tachypnea at triage, chronic ulcers, a history of MRSA colonization or infection, and cellulitis in the past 12 months.
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Why is it important?
This is the first study to examine what factors are associated with failure of oral antibiotics for cellulitis. These factors should be considered by clinicians when they are deciding on the route of therapy for cellulitis.
Perspectives
I hope this will spark further research initiatives towards developing more robust evidence to improve current guidelines for skin and soft tissue infections. This article will better inform clinicians on factors that may predispose to failure with oral antibiotics.
Dr Krishan Yadav
University of Ottawa
Read the Original
This page is a summary of: Predictors of Oral Antibiotic Treatment Failure for Non‐Purulent Skin and Soft Tissue Infections in the Emergency Department, Academic Emergency Medicine, June 2018, Wiley,
DOI: 10.1111/acem.13492.
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