What is it about?
Abeta monomers can protect neurons avoiding memory loss by the expression of BDNF, a neurotrophin that drives cognition
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Why is it important?
This new role of Abeta monomers opens a unexpected crosstalk between insulin receptor and neurotrophic activity
Perspectives
The main perspective concerns neurodegenerative disorders as Alzheimer's disease
Enrico Rizzarelli
Universita degli Studi di Catania
Read the Original
This page is a summary of: Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type-1 insulin-like growth factor receptors in neuronal cells, Aging Cell, November 2017, Wiley,
DOI: 10.1111/acel.12684.
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