Earlobe crease and cardiovascular disease among hemodialysis patients

What is it about?

Do you know earlobe crease? Earlobe creases, also called Frank's sign, are diagonal folds or wrinkles in the skin of the earlobe. They have been identified as surrogate markers for individuals at high risk of cardiovascular disease in the general population. This study is the first to report the prevalence of earlobe creases among hemodialysis patients and to evaluate the fail association between earlobe creases and prevalent cardiovascular disease.

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Why is it important?

Amazingly, there was no association between earlobe creases and prevalent cardiovascular disease in hemodialysis patients. Although the mechanisms leading to the concurrent development of earlobe creases and cardiovascular disease are uncertain, substantial differences in risk factors for cardiovascular disease between hemodialysis patients and the general population may have affected this association.

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