What is it about?
Review on ecological and evolutionary aspects of Agrobacterium pathogenesis
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Why is it important?
Illustrates how even with unusual mechanism by which Agrobacterium tumefaciens causes disease via cross-kingdom horizontal gene transfer, there are clearly common evolutionary ecological themes with this plant pathogen and other facultative disease agents of diverse hosts. Agrobacterium is an exceptional model for studying the trade-offs between the cost of virulence, the benefits of pathogenesis, and the stability of virulence elements for facultative pathogens
Perspectives
Largely the offshoot of experimental and theoretical studies by Tom Platt (now at Kansas State), Elise Morton (now at the University of Florida) and Ian Barton in collaboration with James Bever (now at the University of Kansas). This work was funded through a collaborative grant from the Evolution and Ecology of Infectious Disease program, a visionary joint program between the National Institutes of Health and the National Science Foundation
Clay Fuqua
Indiana University Bloomington
Read the Original
This page is a summary of: Ecological and evolutionary dynamics of a model facultative pathogen: Agrobacterium
and crown gall disease of plants, Environmental Microbiology, December 2017, Wiley,
DOI: 10.1111/1462-2920.13976.
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Contributors
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