What is it about?
Spexin is a recently discovered neuropeptide, which is expressed in different tissues including various parts of brain hippocampus. The analgesic property of spexin was reported for the first time in 2011. This analgesia is not mediated by the opioidergic system because naloxone administration could not prevent the spexin-induced analgesia.
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Why is it important?
Spexin is a recently discovered neuropeptide, which is expressed in different tissues including various parts of brain hippocampus. Toll et.al. reported the analgesic property of spexin for the first time in 2011. They observed that this analgesia is not mediated by the opioidergic system because naloxone administration could not prevent the spexin-induced analgesia
Perspectives
I hope this article provide a way to relieve the pain of humans.
Mahnaz Taherianfard
Shiraz University
Read the Original
This page is a summary of: Synergistic effect of spexin and progesterone on pain sensitivity attenuation in ovariectomized rats, Clinical and Experimental Pharmacology and Physiology, December 2017, Wiley,
DOI: 10.1111/1440-1681.12862.
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