What is it about?

Overlabelling of antibiotic allergy is a serious problem. Most of the labeled antibiotic allergy is just adverse drug reactions. The epidemiological characteristics of children’s adverse reactions to antibiotics are crucial for the appropriate assessment against suspected antibiotic allergies. Our studies investigated epidemiology, focusing on excluding the children with complicated factors, unlike the past studies.

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Why is it important?

Epidemiological data about adverse drug reactions to antibiotics has been unclear because of many confounding factors. This is the first study of ADRs focused only on appropriate antibiotic users in children, although we generally recognize that age and types of drugs are some of the most influential factors in adverse drug reactions. Our study provides epidemiological information that can be used in primary care situations.


We hope that our study will provide a more general understanding of adverse drug reactions to antibiotics, leading to the improvement in approaches to children’s suspected antibiotic allergies.

Kei Sakamoto

Read the Original

This page is a summary of: Type B Adverse Drug Reactions to Antibiotics and Antibiotic Allergy in Infants and Children, Pediatrics International, January 2022, Wiley,
DOI: 10.1111/ped.15126.
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