What is it about?
SKIP is a conserved protein from yeast to plants. We verified that SKIP regulates floral development and environmental fitness via its incorporation into two distinct complexes that regulate gene expression transcriptionally and post-transcriptionally, respectively, in Arabidopsis.
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Why is it important?
SKIP functions as both a splicing factor and transcriptional regulator, and integrates into two distinct complexes to mediate environmental fitness and developmental transition at the transcriptional and post-transcriptional levels of gene expression, respectively, in Arabidopsis. To our knowledge, this study provides the first clear evidence of an instance where one protein integrates into two distinct complexes to mediate different processes at different levels of regulating gene expression.
Perspectives
It is interesting to know the mechanism underlying the incorporation of SKIP into the spliceosome or Paf1c and whether SKIP is required for the integration of environmental fitness and development through balance its incorporation between the spliceosome and Paf1c in plants.
Ligeng Ma
Capital Normal University
Read the Original
This page is a summary of: SKIP regulates environmental fitness and floral transition, respectively, by forming two distinct complexes in Arabidopsis, New Phytologist, June 2019, Wiley,
DOI: 10.1111/nph.15990.
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