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Trypanosoma brucei has six versions of the cap-binding translation initiation factor EIF4E. We here investigated their specialised functions. Unexpectedly, we found that one of them, EIF4E2, binds to, and stabilizes, eight mRNAs that are most abundant when cells are synthesising DNA.

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This page is a summary of: Roles and interactions of the specialized initiation factors EIF4E2, EIF4E5, and EIF4E6 in Trypanosoma brucei: EIF4E2 maintains the abundances of S‐phase mRNAs, Molecular Microbiology, September 2022, Wiley,
DOI: 10.1111/mmi.14978.
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