What is it about?
Human cytomegalovirus (HCMV) acquires its envelope by budding into cellular membranes. We recently showed that HCMV forms multiviral bodies as a so-far undescribed functional egress pathway resulting in the bulk release of large numbers of particles at once. Here we discuss the formation of these structures and the potential implications of this pathway for viral tropism.
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Why is it important?
This review discusses recent findings concerning HCMV egress that might be important in clinical spread pathways.
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This page is a summary of: The unconventional way out—Egress of
through multiviral bodies, Molecular Microbiology, June 2022, Wiley, DOI: 10.1111/mmi.14946.
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