What is it about?
Salmonella biofilm extracellular matrix, particularly one of its components, cellulose, interferes with Salmonella survival inside macrophages and virulence in mice. Its synthesis is controlled by the major extracellular matrix regulator, CsgD, which in turn is under MlrA regulation. In this work, A Salmonella-specific MlrA-like transcription factor, MlrB, is characterized. MlrB is required for macrophages survival. It interferes with CsgD expression inside host cells and synthesis of the extracellular matrix.
Featured Image
Photo by Adrian Lange on Unsplash
Read the Original
This page is a summary of: Balance between bacterial extracellular matrix production and intramacrophage proliferation by a
Salmonella
‐specific SPI‐2‐encoded transcription factor, Molecular Microbiology, August 2021, Wiley,
DOI: 10.1111/mmi.14789.
You can read the full text:
Contributors
The following have contributed to this page
