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FocA belongs to the large FNT (formate-nitrite transporter) family of anion channels and translocates formate bi-directionally across the cytoplasmic membrane of bacteria, archaea and certain single-celled eukaryotes. We show in this study that the soluble N-terminal domain of E. coli FocA is required for both efflux and influx of formate.

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This page is a summary of: The soluble cytoplasmic N‐terminal domain of the FocA channel gates bidirectional formate translocation, Molecular Microbiology, November 2020, Wiley,
DOI: 10.1111/mmi.14641.
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