SMC and the bactofilin/PadC scaffold have distinct yet redundant functions in chromosome segregation and organization in Myxococcus xanthus

What is it about?

The rod-shaped Myxococcus xanthus cells have a unique chromosome organization whereby the chromosome occupies the central part of cells leaving large subpolar regions devoid of DNA. We show that three systems contribute to chromosome segregation and organization in M. xanthus, the ParABS system, the subpolar BacNOP/PadC scaffold, and the SMC condensin-like complex. The BacNOP/PadC scaffold and SMC have different but redundant roles in supporting chromosome segregation and organization by the ParABS system in M. xanthus.

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