Novel coordination of lipopolysaccharide modifications in Vibrio cholerae promotes CAMP resistance

What is it about?

A defining characteristic of Gram-negative bacteria is the presence of a unique glycolipid termed lipopolysaccharide. Antimicrobial peptides that are ubiquitous in nature target lipopolysaccharide eventually leading to cell damage. Here, we describe how Vibrio cholerae, the etiological agent of cholera, remodel their lipopolysaccharide structure to gain resistance to antimicrobial peptides.

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