The inactivation of rfaP, rarA or sspA gene improves the viability of the Escherichia coli DNA polymerase III holD mutant

What is it about?

In this manuscript we describe mutations that improve the viability of a bacterial strain with a crippled DNA polymerase. These mutations restore chromosome replication by stabilizing the defective DNA polymerase on DNA, or preventing competitor repair polymerases from inappropriate binding to replication forks.

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