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The transcriptional regulator RsaL strongly represses phenazine-1-carboxylic acid (PCA) production in the rhizosphere bacterium Pseudomonas aeruginosa PA1201. RsaL negatively regulates phz1 expression and positively regulates phz2 expression. The effect of RsaL on phz1 and phz2 expression is exerted via direct binding at phz1 promoter, the las, rhl and pqs quorum sensing systems, and the ancillary regulator CdpR.

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This page is a summary of: Characterization of the multiple molecular mechanisms underlying RsaL control of phenazine‐1‐carboxylic acid biosynthesis in the rhizosphere bacterium Pseudomonas aeruginosa PA1201, Molecular Microbiology, April 2017, Wiley,
DOI: 10.1111/mmi.13671.
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