Involvement of a conserved GFG motif region in substrate binding by RseP, an E scherichia coli S2P protease

  • RseP-substrate interaction
  • Koichiro Akiyama, Yohei Hizukuri, Yoshinori Akiyama
  • Molecular Microbiology, March 2017, Wiley
  • DOI: 10.1111/mmi.13659

What is it about?

Escherichia coli S2P protease homolog RseP cleaves substrate proteins within the membrane, but the mechanisms underlying its substrate recognition is not fully understood. We showed that the conserved GFG motif region in the first cytoplasmic loop of RseP plays an important role in the proteolytic function of RseP through direct interaction with the substrate

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The following have contributed to this page: Dr Yoshinori Akiyama

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