What is it about?
Fish, as lower vertebrate, the adaptive immunity is influenced by many factors, such as water temperature, photoperiod, pH and dissolved oxygen, etc. Therefore, the innate immunity is of paramount importance for fish to defense against pathogen infection.
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Why is it important?
Molecular characteristics of march5b and co-expression of march5b and tlr7 in response to the infection of Cryptocaryon irritans in the large yellow croaker Larimichthys crocea were investigated.
Perspectives
MARCH members are associated with immune defenses, and MARCH5B probably catalyzes ubiquitination of some proteins of TLR7 signal pathway.
Ms Dongling Zhang
jmu
Read the Original
This page is a summary of: Co-expression ofmarch5bandtlr7in large yellow croakerLarimichthys croceain response toCryptocaryon irritansinfection, Journal of Fish Biology, July 2015, Wiley,
DOI: 10.1111/jfb.12726.
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