What is it about?

Gastroesophageal reflux disease (GERD) is the reflux of gastric contents into the esophagus. The most prominent symptom is ÔheartburnÕ, with or without regurgitation of gastric contents into the mouth [1]. The usual drugs used for GERD are proton pump inhibitors (PPI), which are associated with several complications [2, 3]. A formula developed in our laboratory, for GERD [melatonin (2.5 mg), vitamin B12 (50 lg), vitamin B6 (200 mg), tryptophan (25 mg), methionine (100 mg), betaine (100 mg) and folic acid (10 mg) encapsulated in gelatin capsules)], was prescribed for a patient (with chronic GERD) in an attempt to interrupt the reflux and heal an ulceration of 6 cm in the esophagus. This formulation is based on information existing in scientific literature that melatonin has an inhibitory action on gastric acid secretion [4] and inhibitory activity on biosynthesis of nitric oxide [4]. As the constituents of the formula are natural compounds found in foods, it may present fewer side effects than medications currently used in clinical medicine.

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Why is it important?

This formula cures all types of ulcers (included giant ulcers which is typical of HIV positive patients).


The formula is being produced and sold in USA, with trademark PROTEXID, at the following website: https://www.heranswer.com/products/333-protexid/

Ricardo de Souza Pereira
Universidade Federal do Amapa

Read the Original

This page is a summary of: Regression of an esophageal ulcer using a dietary supplement containing melatonin, Journal of Pineal Research, May 2006, Wiley,
DOI: 10.1111/j.1600-079x.2006.00324.x.
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