Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans

  • Glucokinase activators induce hepatic steatosis
  • Frédéric De Ceuninck, Catherine Kargar, Catherine Ilic, Audrey Caliez, Jean-Olivier Rolin, Thierry Umbdenstock, Cédric Vinson, Murielle Combettes, Brant de Fanti, Elizabeth Harley, Marjorie Sadlo, Anne-Laure Lefèvre, Olivier Broux, Michel Wierzbicki, Jean-Marie Fourquez, Françoise Perron-Sierra, András Kotschy, Alain Ktorza
  • British Journal of Pharmacology, December 2012, Wiley
  • DOI: 10.1111/j.1476-5381.2012.02184.x

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http://dx.doi.org/10.1111/j.1476-5381.2012.02184.x

The following have contributed to this page: Frederic De Ceuninck