What is it about?
To evaluate reproductive endocrine profile, sperm chromosomal abnormalities, and semen quality in patients with chronic hepatitis C.
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Why is it important?
Hepatitis C virus (HCV) is a major cause of chronic liver disease worldwide; >200 million people are infected with HCV, with ≥70% of acute infections progressing to chronic active hepatitis. An estimated 27% of cirrhosis and 25% of hepatocellular carcinoma (HCC) worldwide occur in HCV-infected people. HCV is a RNA virus belonging to the family Flaviviridae , with a diameter of 40–50 nm. The HCV genome is a single-stranded RNA molecule of 9500 kDa that encodes a precursor polypeptide of ≈3000 amino-acid residues .
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This page is a summary of: Evaluation of semen variables, sperm chromosomal abnormalities and reproductive endocrine profile in patients with chronic hepatitis C, BJU International, January 2010, Wiley,
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