What is it about?

To report the results from an Iranian large population-based randomized study of screening using prostate-specific antigen (PSA) to detect prostate cancer.

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Why is it important?

There were 679 000 new cases of prostate cancer worldwide in 2002, making this the fifth most common cancer in the world and the second most common in men (11.7% of new cancer cases overall, 19% in developed countries and 5.3% in developing countries).


Prostate cancer screening using PSA testing is rather peculiar among other screening interventions. PSA is a valid screening test for prostate cancer, which compares favorably with mammography for breast cancer. Several studies have confirmed that PSA-based screening is the most effective screening method; however, most of these studies were done in men referred to urological care settings because of signs and symptoms.

Dr Mohammad Reza Safarinejad
University of Medical Sceices

Read the Original

This page is a summary of: Population-based screening for prostate cancer by measuring total serum prostate-specific antigen in Iran, International Journal of Urology, February 2007, Wiley,
DOI: 10.1111/j.1442-2042.2006.01729.x.
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