What is it about?
This systematic review looked at the impact of utilizing the SMART asthma treatment protocol of low-dose budesonide/formoterol combination with symptom-reactive supplemental dosing. This treatment plan has been reported to reduce exacerbations. We compared this treatment approach to budesonide alone or to lower doses of budesonide/formoterol without supplemental dosing.
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Why is it important?
There is a lack of long-term studies on the impact of the SMART treatment plan despite its broad usage. Our finding found that the SMART plan produces poor day-to-day control of symptoms and is associated with increased inflammation.
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This page is a summary of: The clinical impact of single inhaler therapy in asthma, Clinical & Experimental Allergy, January 2012, Wiley,
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