Structure of NADP+-dependent glutamate dehydrogenase fromEscherichia coli - reflections on the basis of coenzyme specificity in the family of glutamate dehydrogenases

Michael A. Sharkey, Tânia F. Oliveira, Paul C. Engel, Amir R. Khan
  • FEBS Journal, August 2013, Wiley
  • DOI: 10.1111/febs.12439

Why is it important?

Puzzles over varied modes of coenzyme recognition in the GDH family made it important to determine a high-resolution structure for an NADP+ dependent example. The E. coli GDH structure had been studied at low resolution 20 years earlier in a Sheffield-Leeds collaboration but was not taken to high resolution at that time.

The following have contributed to this page: Professor Paul C Engel