What is it about?
The aim of this study was to clarify characteristics of post-encephalopathic epilepsy (PEE) in children after acute encephalopathy with biphasic seizures and late reduced diffusion (AESD), paying particular attention to precise diagnosis of seizure types.
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Why is it important?
We demonstrate seizure characteristics of PEE in children after AESD. Epileptic spasms and startle focal seizures are common seizure types. The specific seizure types may be determined by the pattern of diffuse subcortical white matter injury in AESD and age-dependent reorganization of the brain network.
Perspectives
The most interesting finding in our study is that epileptic spasms and startle seizures as well as focal seizures were common in epilepsy after AESD. This is not consistent with previous studies, which showed without exception that focal seizure was the main seizure type of epilepsy after acute encephalopathy/encephalitis.
Dr Yuji Ito
Nagoya University Graduate School of Medicine
Read the Original
This page is a summary of: Seizure characteristics of epilepsy in childhood after acute encephalopathy with biphasic seizures and late reduced diffusion, Epilepsia, June 2015, Wiley,
DOI: 10.1111/epi.13068.
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Resources
ADORA2A polymorphism predisposes children to encephalopathy with febrile status epilepticus
genetic factors of AESD (Free article)
Excitotoxicity in acute encephalopathy with biphasic seizures and late reduced diffusion.
pathogenesis of AESD (free article)
Epidemiology of acute encephalopathy in Japan, with emphasis on the association of viruses and syndromes.
epidemiology of AESD
Contributors
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