Inhibition of matrix metalloproteinases and toxicity of gold and platinum nanoparticles in L929 fibroblast cells

Masanori Hashimoto, Satoshi Yamaguchi, Jun-Ichi Sasaki, Koji Kawai, Hayato Kawakami, Yasuhiko Iwasaki, Satoshi Imazato
  • European Journal Of Oral Sciences, December 2015, Wiley
  • DOI: 10.1111/eos.12235

Inhibition of matrix metalloproteinases and toxicity of gold and platinum nanoparticles

What is it about?

This study evaluated the inhibition of matrix metalloproteases (MMPs) and cellular responses elicited by gold (Au) and platinum (Pt) nanoparticles (NPs).

Why is it important?

Gold nanoparticles are plausible candidates for MMP inhibitors in resin-bonding materials because they effectively inhibit MMP-1 activity without cytotoxic or inflammatory effects.

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http://dx.doi.org/10.1111/eos.12235

The following have contributed to this page: Dr Satoshi Yamaguchi