What is it about?

Most Asian women desire to have an 'inverted triangle' appearance for face. This has led to an increasing trend of giving a large volume bolus (LVB) injection in the chin for its lengthening. HA dermal fillers are very popular for facial contouring and reshaping, including the chin area. Filler injection in the submental area has been a popular method to lengthen the chin. However placing a large bolus of HA filler material at one place can present as the formation of nodule after injection. This paper presents a case of a nodule formation in the submental area of chin after injection of a single large volume bolus of filler. The nodule was injected with Hyaluronidase about three months after its appearance and a near-complete improvement was seen immediately. Complete disappearance of the nodule was seen at the follow-up after ten days.

Featured Image

Why is it important?

Large-volume bolus of HA filler can give rise to the formation of non-inflammatory nodules after filler injection in the immediate post-injection period. Knowledge of the type of filler material and presenting features can help in instituting the correct line of treatment for the resolution of signs and symptoms.


This paper gives a good perspective of managing a post HA filler nodule and also gives a suggestion of not exceeding the volume of single bolus to above 0.5 ml.

Dr Krishan Mohan Kapoor
Fortis Hospital, Mohali, India

Read the Original

This page is a summary of: Management of Non‐inflammatory Nodule in Chin after a large‐volume bolus injection of Hyaluronic Acid Filler, Dermatologic Therapy, April 2020, Wiley,
DOI: 10.1111/dth.13424.
You can read the full text:



The following have contributed to this page